NBA DFS Picks: FanDuel Plays and Strategy for Monday, December 22

Unlock elite NBA DFS insights by exploring RotoWire's expert projections, injury updates and value picks to dominate tonight’s FanDuel slate.
NBA DFS Picks: FanDuel Plays and Strategy for Monday, December 22
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After a strong Sunday night on FanDuel, we turn the page to a pivotal seven-game NBA DFS slate as the final full week of the 2025 calendar begins. Using industry-leading NBA projections, this breakdown scans salaries, game environments, and late-breaking news from the NBA injury report to uncover both elite plays and value targets. DFS success hinges on monitoring NBA lineups, injury replacements, and matchup-driven opportunity across the slate.

Try our FanDuel NBA Lineup Optimizer to discover more expert recommendations, customize the player pool, set exposure percentage and mass-enter DFS lineups.

NBA Games Today

For the latest spreads and over-unders, visit RotoWire's NBA Odds page. There, you can also find player props, futures, picks articles and sportsbook bonus codes.

The UTA/DEN game has the highest total of the evening, but the massive point spread should be some cause for concern. The DAL/NOP contest also has a high total, and I'm a bigger fan of the closer margin, as well as the potential Dallas injury values. Although the IND/BOS total is low, the potential absences in Boston should reveal some smash-value opportunities if the current injury tags hold up.

NBA Injury Report

For all the latest updates, visit RotoWire's NBA Injury News page and our comprehensive NBA Injury Report. Below are some of the most recent and relevant injuries for Monday. Keep in mind that this is not a complete list. Use your best judgment when evaluating ongoing injury scenarios elsewhere on the slate.

CHA Ryan Kalkbrenner (elbow) - DOUBTFUL

CHA Collin Sexton (quad) - QUESTIONABLE

The Hornets will likely roll with Moussa Diabate ($3,900) in place of Kalkbrenner, and Tre Mann ($3,600) could see more run with the second unit if Sexton is sidelined.

CLE Evan Mobley (calf) - OUT

Mobley will remain out for two more weeks, with Dean Wade ($4,000) seeing the most time as his direct replacement.

BOS Jaylen Brown (illness) - QUESTIONABLE

BOS Jordan Walsh (illness) - QUESTIONABLE

Both players are battling illness, and their status for Monday is unclear. We'll see more action from Sam Hauser ($4,100) and Josh Minott ($3,900) if the tags hold.

DAL Cooper Flagg (back) - QUESTIONABLE

With Klay Thompson (knee) and Max Christie (illness) also questionable,  it's anyone's guess who will show up in the first unit. Wait until lineup lock for things to clear up in this spot.

UTA Lauri Markkanen (groin) - QUESTIONABLE

UTA Kevin Love (rest) - OUT

Love will rest after a sharp game during Markkanen's absence. Kyle Filpowski ($5,800) recently ceded time to Brice Sensabaugh ($4,000), but I'd use caution in a scenario where production might not be enough to be relevant. 

DEN Peyton Watson (side) - QUESTIONABLE

It's times like these when the Nuggets miss Aaron Gordon (hamstring). I expect Tim Hardaway ($4,200) and Bruce Brown ($4,600) to fill in if Watson misses.

MEM Ja Morant (ankle) - OUT

MEM  Brandon Clarke (calf) - OUT

MEM Vince Williams (knee) - OUT

MEM Zach Edey (ankle) - OUT

Cam Spencer ($6,500) will be a fixture at point guard during this game, and Santi Aldama ($6,800) will contribute in the frontcourt. It's also a prime spot for Jaren Jackson ($7,700) to show some leadership and post a significant number.

OKC Chet Holmgren (back) - QUESTIONABLE

OKC Isaiah Hartenstein (leg) - OUT

With a host of other players questionable, the Thunder may have to dig deep to fill in the backcourt. Kenrich Williams ($3,700) could be the surprise producer in this spot.

ORL Jalen Suggs (hip) - DOUBTFUL

OrRL Franz Wagner (ankle) - OUT

These absences should have the greatest impact on the backcourt, where Tyus Jones ($3,700) and Anthony Black ($6,900) are expected to see increased roles.

POR Jerami Grant (Achilles) - QUESTIONABLE

Kris Murray ($4,000) should see a usage bump if Grant is ruled out.

Elite NBA DFS Picks

We see some usual suspects atop the player pool with $10k-plus salaries, and all five of them are healthy. Of the group, Shai Gilgeous-Alexander ($10,800) stands out in a spot where he may have to do a little more to offset potential frontcourt absences. The exploitable spot for Nikola Jokic ($12,700) may also be too good to pass up, although you'll have to pay a premium for his services. Cade Cunningham ($10,500) is also in a good spot, although I would take SGA over Cunningham if I am spending in this range. I'm usually not one to call Anthony Davis' ($10,500) number, but this could turn into a great spot to use him against a team he called home for several seasons. I'd exclude Paolo Banchero ($10,200) as this salary is too high today.

There are some injury concerns at the $9k level, but swapping in Donovan Mitchell ($9,600) could be a path to lower rostership. In the $8k range, Jamal Murray ($8,700) stands out as a good candidate, and I will happily move to Pascal Siakam ($8,600) if Jaylen Brown stays sidelined for the Celtics.

NBA DFS Chalk and Mid-Range Targets

Derrick White, BOS ($7,900) vs. IND

If Brown and Walsh are both out, White is almost a no-brainer for this slate. I'm also fine with him independent of these absences, so he's someone you can slot in early. He's enjoyed some massive totals over the past week, including a career-high nine three-pointers against the Heat.

Jimmy Butler, GSW ($7,800) vs. ORL

Butler played exceptionally well during the two-game set against Phoenix, halting a string of games where his shot needed some tinkering. I like his spot against the Magic tonight, and he could find some mid-range success against a depleted backcourt if he can keep his shot dialed in. Desmond Bane is no slouch defensively, but Butler was able to post 33 points in his last game against the Magic. I'll run with that kind of data.

Shaedon Sharpe, POR ($7,500) vs. DET

The Pistons will travel 2,400 miles to face Portland, and although Detroit is fully healthy, Sharpe is on a nice run of production and will be tough to stop. He just finished a brilliant two-game set against the Kings, and although the Pistons are a stiffer test, Sharpe will do well if he stays hot.

Jarrett Allen, CLE ($6,700) vs. CHA

Allen has been a common add amid Mobley's absence, and he has the distinct advantage of dual eligibility at PF working in his favor. It makes him a valuable commodity because we don't need to use the center position to add him, and the injury to Kalkbrenner also adds to his potential value.

Donovan Clingan, POR ($6,500) vs. DET

We already mentioned Sharpe, but the duel between Clingan and Jalen Duren will be interesting. Duren has been banged up recently but is expected to play, so it could be advantage Clingan if Duren's rebound ability is diminished in any way. Clingan also played well against the Kings, so he's hoping to keep the good vibes going.

Cedric Coward, MEM ($6,000) @ OKC

The Thunder will have some frontcourt deficiencies tonight, and although Aldama is the best value choice for the Grizzlies, Coward may end up being worth $6,000. He'll be slightly contrarian among Memphis' other replacement options, but I view him as a decent tournament alternative.

NBA DFS Value Plays

The injury section is chock-full of our best values, but here are a few additional players to help out your bottom line.

Toumani Camara, POR ($5,900) vs. DET - Solid scoring option who is trending up

Ausar Thompson, DET ($5,500) @ POR - Should step in and contribute in the second half

Hugo Gonzalez, BOS ($4,700) vs. IND - Just logged first start, and is an option if Brown is out

The author(s) of this article may play in daily fantasy contests including – but not limited to – games that they have provided recommendations or advice on in this article. In the course of playing in these games using their personal accounts, it's possible that they will use players in their lineups or other strategies that differ from the recommendations they have provided above. The recommendations in this article do not necessarily reflect the views of RotoWire.
ABOUT THE AUTHOR
Jeff has provided sports content for numerous sports outlets and has played fantasy sports since scores had to be tabulated via newspaper. He started working with RotoWire in 2017. Originally from South Carolina, he's a lifelong Clemson fan now enjoying the sun in Los Angeles.
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