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Giants vs Chiefs Odds, Lines, Spreads & Totals 2025

Chiefs
Giants
Sunday September 21, 2025 at 8:20 PM ET
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KC
Chiefs Injury Report
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NYG
Giants Injury Report
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KC
Chiefs Lineup
Inactives
NYG
Giants Lineup
Inactives
KC
Chiefs News
#3 WR
Tyquan Thornton: Leads KC in receiving Sunday
Sep 21st
Thornton finished with five receptions on nine targets for 71 yards and a touchdown in Sunday's 22-9 win over the Giants.
#1 TE
Travis Kelce: Held to 26 yards on SNF
Sep 21st
Kelce brought in four of seven targets for 26 yards in Sunday's 22-9 win over the Giants.
#2 WR
Hollywood Brown: Draws key penalty in SNF win
Sep 21st
Brown finished with four receptions on six targets for 42 yards in Sunday's 22-9 win over the Giants.
#1 K
Harrison Butker: Inconsistency continues in Week 3
Sep 21st
Butker went 3-for-4 on field-goal attempts and 1-for-2 on extra-point tries in Sunday's 22-9 win over the Giants.
#1 RB
Isiah Pacheco: Leads backfield with 45 yards
Sep 21st
Pacheco took 10 carries for 45 yards and caught his only target for three yards in Sunday's 22-9 win over the Giants.
#1 QB
Patrick Mahomes: Leads KC to first victory
Sep 21st
Mahomes completed 22 of 37 pass attempts for 224 yards and a touchdown while rushing five times for two yards in Sunday's 22-9 win over the Giants.
#5 WR
Jalen Royals: Pro debut on tap
Sep 21st
Royals (knee) is active for Sunday's game at the Giants, Matt McMullen of the Chiefs' official site reports.
#8 WR
Rashee Rice: Returning to team facility
Sep 21st
Rice, who is continuing to serve a suspension for the first six games of the season, will be able to return to Chiefs team facilities in Week 4, Ian Rapoport of NFL Network reports.
#1 WR
Xavier Worthy: Won't play Sunday
Sep 20th
Worthy (shoulder) has been ruled out for Sunday night's game against the Giants.
#2 RCB
Kristian Fulton: Won't play in Week 3
Sep 19th
Fulton (ankle) has been ruled out ahead of Sunday's matchup against the Giants.
#1 RDE
Mike Danna: Out for Week 3
Sep 19th
Danna (quadriceps) has been ruled out ahead of Sunday's matchup against the Giants.
#2 TE
Noah Gray: One catch in loss
Sep 16th
Gray caught one of five targets for one yard in Sunday's 20-17 loss to the Eagles.
#1 MLB
Nick Bolton: Six tackles in Super Bowl rematch
Sep 16th
Bolton finished Sunday's 20-17 loss to the Eagles with six tackles (three solo).
#7 WR
Nikko Remigio: Snares lone target against Philly
Sep 16th
Remigio reeled in his only target for 21 yards during Sunday's 20-17 loss against the Eagles.
#3 RB
Brashard Smith: Tallies first career carry
Sep 16th
Smith accrued one rush for two yards and failed to gather his lone target during Sunday's 20-17 loss to the Eagles.
#4 WR
JuJu Smith-Schuster: Minimal output versus Eagles
Sep 16th
Smith-Schuster recorded one reception (on three targets) for five yards during Sunday's 20-17 loss to the Eagles.
#2 RB
Kareem Hunt: Gains 34 yards on nine touches
Sep 14th
Hunt took eight carries for 31 yards and caught his only target for three yards in Sunday's 20-17 loss to the Eagles.
#4 RB
Elijah Mitchell: Won't play versus Eagles
Sep 14th
Mitchell (coach's decision) has been ruled out for Kansas City's matchup versus the Eagles on Sunday.
#1 WLB
Drue Tranquill: Upgrades to full practice Thursday
Sep 11th
Tranquill (knee) was a full participant in Thursday's practice.
#1 DT2
Omarr Norman-Lott: Practices in full Wednesday
Sep 10th
Norman-Lott (ankle) was a full participant at practice Wednesday.
#1 SS
Jaden Hicks: Sees snaps at slot Week 1
Sep 7th
Hicks finished Friday's 27-21 loss to the Chargers with four tackles (three solo).
#1 LDT
Chris Jones: Two tackles vs. Bolts
Sep 7th
Jones recorded two assisted tackles during the Chiefs' 27-21 loss to the Chargers on Friday.
#1 LDE
George Karlaftis: Records Week 1 sack
Sep 7th
Karlaftis notched three tackles (two solo), including 1.0 sacks, in Friday's Week 1 loss to the Chargers.
NYG
Giants News
#2 WR
Wan'Dale Robinson: Held to one catch
Sep 21st
Robinson recorded one catch on four targets for 26 yards in Sunday's 22-9 loss to the Chiefs.
#1 RB
Cam Skattebo: Looks good as lead back
Sep 21st
Skattebo rushed the ball 10 times for 60 yards and a touchdown in Sunday's 22-9 loss to the Chiefs. He added six receptions on eight targets for 61 yards.
#1 QB
Russell Wilson: Abysmal showing against Chiefs
Sep 21st
Wilson completed 18 of 32 passes for 160 yards, no touchdowns and two interceptions in Sunday's 22-9 loss to the Chiefs. He added five rushes for 27 yards.
#1 WR
Malik Nabers: Struggles in primetime
Sep 21st
Nabers recorded two receptions on seven targets for 13 yards in Sunday's 22-9 loss to the Chiefs.
#1 K
Graham Gano: Makes lone FGA
Sep 21st
Gano (groin) made his only field-goal attempt in Sunday's 22-9 loss to the Chiefs.
#2 RB
Tyrone Tracy: Done for night with shoulder injury
Sep 21st
Tracy (shoulder) will not return to Sunday night's game against the Chiefs, Pat Leonard of the New York Daily News reports.
#2 LILB
Demetrius Flannigan-Fowles: No go for Week 3
Sep 21st
Flannigan-Fowles (calf) is inactive for Sunday night's contest against the Chiefs, Dan Salomone of the Giants' official site reports.
#1 LDE
Rakeem Nunez-Roches: Won't play against Kansas City
Sep 21st
Nunez-Roches (foot) has been ruled out for Sunday's game against the Chiefs, Dan Salomone of the Giants' official site reports.
#1 LT
Andrew Thomas: Starting Sunday
Sep 21st
Thomas (foot) is active for Sunday night's contest against the Chiefs, Dan Salomone of the Giants' official site reports.
#6 WR
Gunner Olszewski: Cleared to play against KC
Sep 21st
Olszewski (back) is active for Sunday's game against the Chiefs, Dan Salomone of the Giants' official site reports.
#2 SLB
Chauncey Golston: Inactive for Week 3
Sep 21st
Golston (ankle) is inactive for Sunday night's contest against the Chiefs, Dan Salomone of the Giants' official site reports.
#3 QB
Jameis Winston: Emergency QB vs. Kansas City
Sep 21st
Winston (coach's decision) is inactive but will serve as the Giants' emergency third quarterback against the Chiefs on Sunday, Dan Salomone of the Giants' official site reports.
#1 RILB
Darius Muasau: Won't play Sunday
Sep 19th
Muasau (concussion/eye) has been ruled out ahead of Sunday's matchup against the Chiefs.
#3 WR
Darius Slayton: Cleared for SNF
Sep 19th
Slayton (groin) doesn't have an injury designation for Sunday's game against the Chiefs, Tom Pelissero of NFL Network reports.
#3 LILB
Chris Board: Placed on IR
Sep 16th
The Giants placed Board (chest) on injured reserve Tuesday, Dan Salomone of the Giants' official site reports.
#1 SCB
Dru Phillips: Shines with INT in Week 2
Sep 15th
Phillips registered 11 tackles (eight solo) and two pass defenses, including an interception, in Sunday's overtime loss to the Cowboys.
#1 LCB
Paulson Adebo: Racks up 13 stops in Week 2
Sep 15th
Adebo posted 13 tackles (11 solo) and a defensed pass Sunday in an overtime loss to the Cowboys.
#1 SS
Tyler Nubin: Tallies five stops Week 2
Sep 15th
Nubin recorded five tackles (all solo) in Sunday's overtime defeat against Dallas.
#1 LILB
Bobby Okereke: Racks up double-digit stops again
Sep 15th
Okereke finished with 10 tackles (four solo) and a defensed pass in Sunday's Week 2 overtime loss to the Cowboys.
#2 TE
Daniel Bellinger: Gets zero targets Week 2
Sep 15th
Bellinger did not receive any passing targets Sunday in an overtime defeat against Dallas.
#1 TE
Theo Johnson: Picks up production Week 2
Sep 15th
Johnson caught four of five targets for 34 yards in Sunday's overtime loss to the Cowboys.
#4 WR
Jalin Hyatt: Doesn't see field again Week 2
Sep 15th
Hyatt did not log any snaps Sunday in an overtime loss to Dallas.
#3 RB
Devin Singletary: Nets zero yards in minor role
Sep 15th
Singletary rushed once for four yards and caught his only target for minus-4 yards in Sunday's Week 2 overtime loss to Dallas.
#4 RILB
Micah McFadden: Placed on injured reserve
Sep 11th
The Giants placed McFadden (foot) on injured reserve Thursday.
#1 FS
Jevon Holland: Logs seven tackles
Sep 9th
Holland recorded seven tackles (three solo) and one pass deflection in the Giants' loss to the Commanders.
#1 NT
Dexter Lawrence: Tallies three tackles
Sep 9th
Lawrence logged three tackles in the Giants' loss versus the Commanders on Sunday.
#1 WLB
Brian Burns: Tallies 2.0 sacks Week 1
Sep 8th
Burns registered six tackles (two solo), including 2.0 sacks, in Sunday's loss to the Commanders.
#2 RDE
Darius Alexander: Won't make NFL debut vs. WAS
Sep 7th
Alexander (coach's decision) is inactive for Sunday's game against the Commanders, Dan Salomone of the Giants' official site reports.
#4 TE
Thomas Fidone: Healthy scratch Week 1
Sep 7th
Fidone (coach's decision) is inactive for Sunday's NFC East clash against the Commanders, Dan Salomone of the Giants' official site reports.
#2 QB
Jaxson Dart: Could have role in Week 1 game plan
Sep 7th
Dart will be active as the top backup to Russell Wilson in Sunday's game at Washington, and the Giants could have a package of plays designed for the rookie quarterback, Dan Graziano of ESPN.com reports.