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Giants vs Chargers Odds, Lines, Spreads & Totals 2025

Chargers
24.8 Pts
Giants
18.8 Pts
Sunday September 28, 2025 at 1:00 PM ET
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LAC
Chargers Injury Report
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NYG
Giants Injury Report
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LAC
Chargers Lineup
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NYG
Giants Lineup
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LAC
Chargers News
#2 FS
Elijah Molden: Makes return to practice
Sep 24th
Molden (hamstring) was a limited participant at practice Wednesday.
#1 RCB
Cam Hart: Looking good for Sunday
Sep 24th
Hart (hip) was a full participant at practice Wednesday.
#5 WR
Derius Davis: Opens week with DNP
Sep 24th
Davis (knee) did not participate in Wednesday's practice.
#1 TE
Will Dissly: Not spotted at practice
Sep 24th
Dissly (knee) is not present at the early portion of Wednesday's practice open to the media, Daniel Popper of The Athletic reports.
#3 RB
Najee Harris: Officially on IR
Sep 24th
The Chargers placed Harris (Achilles) on IR on Wednesday.
#2 SS
Tony Jefferson: Registers five tackles Sunday
Sep 23rd
Jefferson finished with five tackles (three solo) and a defensed pass in Sunday's 23-20 Week 3 win over Denver.
#1 RB
Omarion Hampton: Larger workload on tap
Sep 22nd
Hampton is set to lead the Chargers backfield in the wake of Najee Harris' season-ending torn Achilles, Daniel Popper of The Athletic reports.
#4 WR
Tre' Harris: Just one target Week 3
Sep 22nd
Harris failed to haul in his lone target during the Chargers' 23-20 win over the Broncos on Sunday.
#3 TE
Tyler Conklin: Plays 22 offensive snaps in Week 3
Sep 22nd
Conklin failed to haul in either of his two targets during the Chargers' 23-20 win over the Broncos on Sunday.
#1 LILB
Daiyan Henley: Just four tackles against Denver
Sep 22nd
Henley logged four tackles (two solo) during the Chargers' 23-20 win over the Broncos on Sunday.
#1 SS
Derwin James: All over field in Week 3 win
Sep 22nd
James logged 12 tackles (10 solo), including 1.0 sacks, during the Chargers' 23-20 win over the Broncos on Sunday.
#2 TE
Oronde Gadsden: Impresses in debut
Sep 22nd
Gadsden caught five of his seven targets for 46 yards in the 23-20 win over the Broncos on Sunday.
#1 K
Cameron Dicker: Hits game-winning kick
Sep 21st
Dicker went 3-for-3 on field-goal attempts and made two PATs in Sunday's 23-20 win over the Broncos.
#3 WR
Keenan Allen: Scores yet again
Sep 21st
Allen caught seven of his 11 targets for 65 yards and the game-tying touchdown in the 23-20 win over the Broncos on Sunday.
#2 WR
Quentin Johnston: Leads team in receiving yards
Sep 21st
Johnston tallied six receptions for 89 yards on 10 targets in the 23-20 win over the Broncos on Sunday.
#1 WR
Ladd McConkey: Takes back seat in win
Sep 21st
McConkey caught four of his seven targets for 41 yards in the 23-20 win over the Broncos on Sunday.
#1 QB
Justin Herbert: Stellar in win
Sep 21st
Herbert completed 28 of 47 pass attempts for 300 passing yards to go along with a touchdown and an interception in a 23-20 win over the Broncos on Sunday. He also scrambled twice for six yards.
#1 RG
Mekhi Becton: Done for day
Sep 21st
Becton (concussion) has been ruled out for the remainder of Sunday's game versus the Broncos.
#6 WR
KeAndre Lambert-Smith: Inactive Sunday
Sep 21st
Lambert-Smith is inactive for Sunday's game against the Broncos.
#2 ROLB
Khalil Mack: Out at least four games
Sep 17th
The Chargers placed Mack (elbow) on injured reserve Wednesday.
#1 SCB
Tarheeb Still: Productive in win
Sep 16th
Still logged nine tackles (seven solo) in the Chargers' win over the Raiders on Monday.
#3 LDE
Justin Eboigbe: Returns to game Monday
Sep 15th
Eboigbe has returned to Monday's Week 2 contest against Las Vegas after previously exiting with an ankle injury, Daniel Popper of The Athletic reports.
#3 RILB
Denzel Perryman: Placed on injured reserve
Sep 15th
The Chargers placed Perryman (ankle) on injured reserve Monday.
NYG
Giants News
#1 RILB
Darius Muasau: Still recovering from concussion
Sep 24th
Muasau (concussion) was a limited participant at practice Wednesday, Dan Salomone of the Giants' official site reports.
#3 WR
Darius Slayton: Limited in practice
Sep 24th
Slayton (calf) was a limited practice participant Wednesday, Dan Salomone of the Giants' official site reports.
#1 TE
Theo Johnson: Dealing with toe injury
Sep 24th
Johnson missed Wednesday's practice with a toe injury, Dan Salomone of the Giants' official site reports.
#2 RB
Tyrone Tracy: DNP on Wednesday
Sep 24th
Tracy (shoulder) didn't take part in Wednesday's practice, Dan Salomone of the Giants' official site rpeorts.
#2 QB
Russell Wilson: In backup role for good
Sep 24th
Giants coach Brian Daboll said Wednesday that Wilson will operate as the backup to Jaxson Dart for the rest of the season, Jordan Raanan of ESPN reports.
#1 K
Graham Gano: Stint on IR expected
Sep 24th
The Giants are expected to place Gano (groin) on injured reserve, Jordan Raanan of ESPN.com reports.
#1 WR
Malik Nabers: Sitting out practice Wednesday
Sep 24th
Giants head coach Brian Daboll said Wednesday that Nabers (back) will not participate in practice, Ryan Dunleavy of the New York Post reports.
#1 QB
Jaxson Dart: Officially named starting QB
Sep 24th
Giants head coach Brian Daboll said Wednesday that Dart will be the team's starting quarterback for the rest of the season, beginning with Sunday's contest against the Chargers, Ryan Dunleavy of the New York Post reports.
#1 SCB
Dru Phillips: Notches two defensed passes Week 3
Sep 23rd
Phillips finished Sunday's loss to Kansas City with five tackles (four solo) and two defensed passes.
#1 WLB
Brian Burns: Takes down Mahomes in Week 3 loss
Sep 23rd
Burns notched six tackles (five solo), including 1.0 sacks, and added two defensed passes along with a forced fumble in Sunday's loss to the Chiefs.
#1 LCB
Paulson Adebo: Productive again in Week 3 loss
Sep 23rd
Adebo posted seven tackles (six solo) and a defensed pass Sunday in a loss to Kansas City.
#1 LILB
Bobby Okereke: Steady again Sunday
Sep 22nd
Okereke notched eight tackles (four solo) Sunday in a Week 3 loss to the Chiefs.
#2 TE
Daniel Bellinger: Catches lone target Sunday
Sep 22nd
Bellinger caught his only target for six yards Sunday in a Week 3 loss to the Chiefs.
#3 RB
Devin Singletary: In line for increased role
Sep 22nd
Tyrone Tracy is slated to miss time after dislocating his shoulder in Sunday's loss to the Chiefs, per Jordan Raanan of ESPN.com, so Singletary likely will move up to the Giants' No. 2 RB role.
#2 WR
Wan'Dale Robinson: Held to one catch
Sep 21st
Robinson recorded one catch on four targets for 26 yards in Sunday's 22-9 loss to the Chiefs.
#1 RB
Cam Skattebo: Looks good as lead back
Sep 21st
Skattebo rushed the ball 10 times for 60 yards and a touchdown in Sunday's 22-9 loss to the Chiefs. He added six receptions on eight targets for 61 yards.
#2 LILB
Demetrius Flannigan-Fowles: No go for Week 3
Sep 21st
Flannigan-Fowles (calf) is inactive for Sunday night's contest against the Chiefs, Dan Salomone of the Giants' official site reports.
#1 LDE
Rakeem Nunez-Roches: Won't play against Kansas City
Sep 21st
Nunez-Roches (foot) has been ruled out for Sunday's game against the Chiefs, Dan Salomone of the Giants' official site reports.
#1 LT
Andrew Thomas: Starting Sunday
Sep 21st
Thomas (foot) is active for Sunday night's contest against the Chiefs, Dan Salomone of the Giants' official site reports.
#6 WR
Gunner Olszewski: Cleared to play against KC
Sep 21st
Olszewski (back) is active for Sunday's game against the Chiefs, Dan Salomone of the Giants' official site reports.
#2 SLB
Chauncey Golston: Inactive for Week 3
Sep 21st
Golston (ankle) is inactive for Sunday night's contest against the Chiefs, Dan Salomone of the Giants' official site reports.
#3 QB
Jameis Winston: Emergency QB vs. Kansas City
Sep 21st
Winston (coach's decision) is inactive but will serve as the Giants' emergency third quarterback against the Chiefs on Sunday, Dan Salomone of the Giants' official site reports.
#3 LILB
Chris Board: Placed on IR
Sep 16th
The Giants placed Board (chest) on injured reserve Tuesday, Dan Salomone of the Giants' official site reports.
#1 SS
Tyler Nubin: Tallies five stops Week 2
Sep 15th
Nubin recorded five tackles (all solo) in Sunday's overtime defeat against Dallas.
#4 WR
Jalin Hyatt: Doesn't see field again Week 2
Sep 15th
Hyatt did not log any snaps Sunday in an overtime loss to Dallas.
#3 RILB
Micah McFadden: Placed on injured reserve
Sep 11th
The Giants placed McFadden (foot) on injured reserve Thursday.
#5 WR
Xavier Gipson: Stays in Big Apple with Big Blue
Sep 11th
Gipson was claimed off waivers by the Giants on Thursday, Ian Rapoport of NFL Network reports.