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Chargers vs Chiefs Odds, Lines, Spreads & Totals 2025

Chiefs
24.0 Pts
Chargers
21.5 Pts
Friday September 5, 2025 at 8:00 PM ET
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KC
Chiefs Injury Report
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LAC
Chargers Injury Report
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KC
Chiefs Lineup
Inactives
    None reported yet.
LAC
Chargers Lineup
Inactives
    None reported yet.
KC
Chiefs News
#6 TE
Jake Briningstool: Misses practice Sunday
Jul 27th
Briningstool (hamstring) didn't participate in Kansas City's practice Sunday, Pete Sweeney of ArrowheadPride.com reports.
#1 RT
Jawaan Taylor: Returns from PUP
Jul 27th
Taylor (undisclosed) was activated from the active/PUP list Sunday, Pete Sweeney of ArrowheadPride.com reports.
#7 TE
Tre Watson: Activated off PUP list
Jul 27th
The Chiefs activated Watson (undisclosed) off the active/PUP list Sunday, Pete Sweeney of ArrowheadPride.com reports.
#4 RB
Brashard Smith: Mixing in with starters a bit
Jul 24th
Kansas City's first-team offense featured a "sprinkling" of Smith on Thursday, according to Matt Derrick of ChiefsDigest.com.
#3 RB
Elijah Mitchell: Getting some first-team looks
Jul 24th
Mitchell, Isiah Pacheco and Kareem Hunt got first-team snaps Thursday, along with a "sprinkling" of rookie Brashard Smith, according to Matt Derrick of ChiefsDigest.com.
#5 WR
Jalen Royals: Sees some first-team reps
Jul 24th
Royals logged most of his repetitions during Wednesday's practice with the first-team offense, Nate Taylor of ESPN.com reports.
#3 TE
Jared Wiley: Past knee injury
Jul 23rd
Wiley (knee) has participated in training camp practices this week, Matt McMullen of the Chiefs' official site reports.
#1 LT
Josh Simmons: Taking first-team reps
Jul 22nd
Simmons (knee) was taking first-team reps at left tackle during training camp Tuesday, Sam McDowell of The Kansas City Star reports.
#1 TE
Travis Kelce: Ready for 13th season
Jul 22nd
Kelce participated in Tuesday's training camp practice.
#1 WR
Rashee Rice: Full go for start of camp
Jul 22nd
Rice (knee) will be a full participant in training camp as he awaits news on a potential suspension, Jenna West of The Athletic reports.
#13 WR
Hal Presley: Latching on with KC
Jul 21st
Presley is signing with the Chiefs on Monday, Aaron Wilson of KPRC 2 Houston reports.
#1 RCB
Kristian Fulton: Placed on PUP list
Jul 20th
Fulton (undisclosed) was placed on the active/PUP list by the Chiefs on Sunday, Charles Goldman of AtoZSports.com reports.
#1 LDE
George Karlaftis: Lands big extension from KC
Jul 20th
Karlaftis agreed to a four-year, $93 million contract with the Chiefs on Sunday, Adam Schefter of ESPN reports.
#1 RG
Trey Smith: Signing lucrative extension
Jul 15th
Smith is slated to sign a four-year extension with Kansas City, Ian Rapoport of NFL Network reports.
LAC
Chargers News
#3 WR
Tre Harris: Strong practice Monday
Jul 29th
Harris turned in one of his best practices of training camp on Monday, according to Daniel Popper of The Athletic.
#5 WR
Jalen Reagor: Misses another practice
Jul 28th
Reagor (lower body) isn't practicing Monday, Kris Rhim of ESPN.com reports.
#1 LT
Rashawn Slater: Gets historic contract extension
Jul 27th
Slater agreed to a four-year, $114 million contract extension with the Chargers on Sunday, Adam Schefter of ESPN reports.
#10 WR
JaQuae Jackson: Bolts to Los Angeles
Jul 25th
The Chargers signed Jackson to a contract Friday.
#1 LG
Bradley Bozeman: Starting spot unclear
Jul 24th
Bozeman has been rotating between left guard and center with Zion Johnson every day at training camp, Daniel Popper of The Athletic reports.
#6 WR
KeAndre Lambert-Smith: Flashing potential as outside WR
Jul 24th
Lambert has been an early standout for the Chargers through the first week of training camp, Daniel Popper of The Athletic reports.
#3 RT
Savion Washington: Reverts to PUP list
Jul 23rd
Washington (undisclosed) reverted to the Chargers' reserve/PUP list Wednesday, Aaron Wilson of KPRC 2 Houston reports.
#5 RB
Nyheim Hines: Joins Bolts
Jul 21st
Hines signed with the Chargers on Monday, Adam Schefter of ESPN reports.
#2 WR
Quentin Johnston: Battling to keep X receiver spot
Jul 21st
Chargers offensive coordinator Greg Roman said Johnston, Tre Harris and Jalen Reagor can play the X receiver spot, Alex Insdorf of BoltBeat.com reports.
#2 FS
Elijah Molden: Returns to practice
Jul 20th
Molden (knee) was activated from the active/PUP list Sunday, Aaron Wilson of KPRC 2 Houston reports.
#8 WR
Jaylen Johnson: Back in action
Jul 20th
Johnson (undisclosed) was activated from the active/PUP list Sunday, Aaron Wilson of KPRC 2 Houston reports.
#1 QB
Justin Herbert: Sharp to begin training camp
Jul 17th
Herbert looked in midseason form on the first day of training camp Thursday, Eric Smith of the Chargers' official site reports.
#1 RB
Najee Harris: Officially placed on NFI list
Jul 17th
Harris (eye) was placed on the active/non-football injury list by the Chargers on Thursday.